What does this Organic Chemistry II: Reactions cheat sheet cover?

It has 10 sections: Aromaticity, EAS Core, Directing Effects, Carbonyl Addn, Aldehydes/Ketones, Carboxylic Derivs, Grignard/Redox, Enolates/Condens, Amines and IR/NMR. Together they cover the topics a typical Organic Chemistry II: Reactions exam tests, including aromaticity and electrophilic aromatic substitution, directing effects, carbonyl nucleophilic addition and aldehyde and ketone reactions.

Is the organic chemistry reactions cheat sheet free?

The first part is free to read on this page, with no account needed. The full sheet opens in the app with Unlimited ($4.99 a month or $19 for a semester), where you can edit it, print it or save it as a PDF. It is one US Letter page and prints cleanly in black and white or colour.

Can I bring this Organic Chemistry II: Reactions cheat sheet to my exam?

Only if your course allows a note sheet, so check the syllabus. This one is a single US Letter page. If your exam allows a different size, such as a 3x5 or 4x6 index card or one page front and back, Cheat Sheet AI makes one at exactly that size from your own lecture notes.

The sheet was written by our engine from a standard course outline, then a second model fact-checked every formula and statement against it; it corrected 9 statements before publishing. Notation and emphasis vary between courses, so check it against your own lecture notes.

Can I make a Organic Chemistry II: Reactions sheet from my own notes?

Yes. Upload your lecture slides, notes or study guide and Cheat Sheet AI writes a sheet in your course's notation, sized to exactly the space your exam allows. Your first sheets are free.

Chemistry & BioOrganic Chemistry II: Reactions

Organic Chemistry Reactions Cheat Sheet — 1-page PDF

Aromaticity, carbonyl chemistry, enolates, amines, oxidation/reduction, IR/NMR. The whole course on one dense, printable page for your midterm or final, with every formula typeset and worked examples where they help.

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For a specific exam: Organic Chemistry II Midterm study sheet, Organic Chemistry II Final exam study sheet.

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10 sections11 topics
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Preview of the one-page Organic Chemistry II: Reactions cheat sheet: Aromaticity, carbonyl chemistry, enolates, amines, oxidation/reduction, IR/NMR — the whole course, one page

On the sheet

What’s on it

The topics a typical Organic Chemistry II: Reactions exam tests, all on the one page.

Aromaticity and electrophilic aromatic substitution
Directing effects
Carbonyl nucleophilic addition
Aldehyde and ketone reactions
Carboxylic acid derivatives reactivity
Grignard reagents
Oxidation and reduction reagents
Aldol and Claisen condensations
Enolates
Amines
Spectroscopy: IR and NMR key values

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The free part of the sheet, section by section. Unlock the full sheet to read the rest, edit any block, and print it or save it as a PDF.

01Aromaticity

Aromatic: Cyclic, planar, fully conjugated, $4 n + 2$ $π$ electrons (Hückel). Stabilized.
Antiaromatic: Cyclic, planar, fully conjugated, $4 n$ $π$ electrons. Destabilized.
Nonaromatic: Fails cyclic / planar / fully conjugated requirement.

Hfckel

4 n + 2 π e^{-}

Aromatic if cyclic, planar, conjugated; $n = 0, 1, 2, \dots$

Aromaticity checklist

Test	Need
Ring	cyclic
Geometry	planar
Orbitals	continuous p overlap
Electrons	$4 n + 2$
Common fail	sp $3$ atom breaks conjugation

Watch out:Count $π$ e $^{-}$ only: each double bond = $2$ , anion lone pair in p orbital = $2$ , cation = $0$ ; heteroatom lone pair may or may not count if needed for conjugation.

02EAS Core

Electrophilic aromatic substitution (EAS): Replace ring H by E $^{+}$ while retaining aromaticity.

03Directing Effects

Deactivating: Decreases ring rate toward EAS vs benzene.

Ex.Predict major nitration site of anisole.

$- OCH X_{3}$ is strong o/p director; para usually major over ortho (sterics).

Watch out:Halogens are o/p directors but deactivating: lone-pair donation vs inductive withdrawal.

04Carbonyl Addn

Nucleophilic addition: $π$ bond of carbonyl accepts Nu $^{-}$ ; forms tetrahedral alcohol / alkoxide product after protonation.

Carbonyl reactivity

R X_{2} C = O + Nu X^{-} R X_{2} C (O -) Nu R X_{2} C (OH) Nu

Aldehydes react faster than ketones: less steric + less electron donation.

Common additions

Reagent	Product
$NaBH X_{4}$	alcohol from aldehyde/ketone
$LiAlH X_{4}$	alcohol; also reduces derivatives
$RMgX$ , $RLi$	C--C bond; alcohol after workup
$HCN$	cyanohydrin
$ROH, H X^{+}$	hemiacetal / acetal
$RNH X_{2}$	imine
$R X_{2} NH$	enamine

05Carboxylic Derivs

General

RCOX + Nu X^{-} RCONu + X X^{-}

X = leaving group; addition--elimination.

Reactivity order

Most reactive	Least reactive
acyl chloride > anhydride > ester > amide > carboxylate

Order: $RCOCl > (RCO) X_{2} O > RCOOR X^{'} > RCONR X_{2} ≫ RCO X_{2} X^{-}$

Derivative conversions

Reagent	Typical use
$H X_{2} O$ / $OH X^{-}$	hydrolysis
$ROH$	esterification / transesterification
$NH X_{3}$ / amine	amide
$LiAlH X_{4}$	alcohol / amine reduction
$DIBAL - H$	ester $\to$ aldehyde (low $T$ )

Watch out:Direct acid + alcohol Fischer esterification is equilibrium; drive with excess alcohol or remove water.

06Grignard/Redox

Grignard reagent: Organomagnesium halide, $RMgX$ ; strong base and nucleophile.

07Enolates/Condens

Crossed aldol: Two different carbonyls; best when only one has $α$ -H or one is formaldehyde.

Watch out:Claisen base must match leaving group (e.g. $EtO X^{-}$ for ethyl ester) to avoid transesterification.

08Amines

Amine basicity: Lone pair on N accepts $H X^{+}$ ; aliphatic amines usually more basic than aniline (lone pair delocalization in aniline).

Amine reactions

Reaction	Product
$RNH X_{2} + R X^{'} X$	alkylated amine (can overalkylate)
$R X_{2} NH + R X^{'} X$	tertiary amine
$RNH X_{2} + RCHO$	imine
$R X_{2} NH + RCHO$	enamine
$RNH X_{2} + TsCl$	sulfonamide

Aniline to diazonium

ArNH X_{2} NaNO X_{2} / HCl, 0 - 5 X_{\circ} X_{2}^{2 \circ} C ArN X_{2} X^{+}

Aryl diazonium = versatile intermediate for substitution / Sandmeyer.

Watch out:Primary amines give imines; secondary amines give enamines. Tertiary amines cannot form imines (no N--H).

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EAS Core

EAS pattern
General EAS
Common EAS reagents

Directing Effects

Directors
Activating

Carbonyl Addn

Aldehydes/Ketones

Key reactions
Imines
Enamine
Acetal/ketal terms

Carboxylic Derivs

Acyl substitution

Grignard/Redox

Grignard + carbonyl
Grignard outcomes
Key restriction
Reductions

Enolates/Condens

Enolate
Aldol
Claisen

Amines

IR/NMR

IR key peaks
H NMR quick
Coupling
C NMR

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About the Organic Chemistry II: Reactions sheet and making your own.

What does this Organic Chemistry II: Reactions cheat sheet cover?: It has 10 sections: Aromaticity, EAS Core, Directing Effects, Carbonyl Addn, Aldehydes/Ketones, Carboxylic Derivs, Grignard/Redox, Enolates/Condens, Amines and IR/NMR. Together they cover the topics a typical Organic Chemistry II: Reactions exam tests, including aromaticity and electrophilic aromatic substitution, directing effects, carbonyl nucleophilic addition and aldehyde and ketone reactions.
Is the organic chemistry reactions cheat sheet free?: The first part is free to read on this page, with no account needed. The full sheet opens in the app with Unlimited ($4.99 a month or $19 for a semester), where you can edit it, print it or save it as a PDF. It is one US Letter page and prints cleanly in black and white or colour.
Can I bring this Organic Chemistry II: Reactions cheat sheet to my exam?: Only if your course allows a note sheet, so check the syllabus. This one is a single US Letter page. If your exam allows a different size, such as a 3x5 or 4x6 index card or one page front and back, Cheat Sheet AI makes one at exactly that size from your own lecture notes.
How accurate is it?: The sheet was written by our engine from a standard course outline, then a second model fact-checked every formula and statement against it; it corrected 9 statements before publishing. Notation and emphasis vary between courses, so check it against your own lecture notes.
Can I make a Organic Chemistry II: Reactions sheet from my own notes?: Yes. Upload your lecture slides, notes or study guide and Cheat Sheet AI writes a sheet in your course's notation, sized to exactly the space your exam allows. Your first sheets are free.

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